Description

1-(Phenylsulfonyl)-6-Chloro-2-Iodo-5-Azaindole is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound matters because it provides a versatile scaffold for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Serves as a precursor in the creation of novel herbicides and fungicides.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target engagement.
• Material Science: Potential intermediate for the synthesis of organic electronic materials and advanced polymers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services.

Basic Information

Product Name	1-(Phenylsulfonyl)-6-Chloro-2-Iodo-5-Azaindole
CAS No.	1227267-17-5
Molecular Formula	C13H7ClIN2O2S
Molecular Weight	417.63 g/mol
Synonyms	6-Chloro-2-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 6-chloro-2-iodo-1-(phenylsulfonyl)-; 6-Chloro-2-iodo-1-(benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1-Benzenesulfonyl-6-chloro-2-iodo-1H-pyrrolo[2,3-b]pyridine; 6-Chloro-2-iodo-1-(phenylsulfonyl)-7-azaindole; 1-(Phenylsulfonyl)-6-chloro-2-iodo-7-azaindole; 6-Chloro-2-iodo-1-tosyl-1H-pyrrolo[2,3-b]pyridine (common misnomer); 5-Azaindole, 6-chloro-2-iodo-1-(phenylsulfonyl)-
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulfonyl)-6-Chloro-2-Iodo-5-Azaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.