Description

4-Oxo-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-2-Carboxylic Acid is a high-value heterocyclic building block featuring a fused cyclopentane-thiophene scaffold with a carboxylic acid functional group. This compound is essential for advanced organic synthesis, particularly in the development of novel pharmaceuticals and agrochemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Serves as a core structure for developing novel herbicides, fungicides, and insecticides with potentially enhanced efficacy and selectivity.
• Material Science Precursor: Used in the synthesis of organic semiconductors, conductive polymers, and non-linear optical (NLO) materials due to its electron-rich thiophene moiety.
• Ligand and Catalyst Development: The carboxylic acid group allows for derivatization into chelating ligands for metal-organic frameworks (MOFs) or homogeneous catalysis.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including cycloaddition reactions and heterocycle functionalization.

Basic Information

Product Name	4-Oxo-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-2-Carboxylic Acid
CAS No.	1227210-42-5
Molecular Formula	C8H6O3S
Molecular Weight	182.20 g/mol
Synonyms	4-Oxo-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxylic acid; 4-Oxo-4,5,6,7-tetrahydrobenzo[b]thiophene-2-carboxylic acid; Cyclopenta[b]thiophene-2-carboxylic acid, 4,5,6,7-tetrahydro-4-oxo-; 2-Carboxy-4,5,6,7-tetrahydro-4-oxocyclopenta[b]thiophene; 4-Oxo-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxylate (anion form); 1227210-42-5; 4-Oxo-5,6-dihydro-4H-cyclopenta[b]thiophene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Oxo-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.