Description

1-(6-Amino-3,3-Dimethylindolin-1-Yl)Ethanone Hydrochloride is a high-purity, synthetically derived indoline derivative, serving as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile building block in organic synthesis. Its value lies in its functionalized indoline core, which is integral to constructing complex molecules with potential biological activity. This compound is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Organic Synthesis: Serves as a versatile precursor for constructing complex heterocyclic compounds and fine chemicals.
• Process Development: Employed in scaling up synthetic routes for active pharmaceutical ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Biochemical Research: Potential use as a probe or ligand in biochemical assays due to its specific molecular scaffold.

Basic Information

Product Name	1-(6-Amino-3,3-Dimethylindolin-1-Yl)Ethanone Hydrochloride
CAS No.	1226815-20-8
Molecular Formula	C12H17ClN2O
Molecular Weight	240.73 g/mol
Synonyms	1-(6-Amino-3,3-dimethyl-2,3-dihydro-1H-indol-1-yl)ethanone hydrochloride; 1-Acetyl-6-amino-3,3-dimethylindoline hydrochloride; 6-Amino-3,3-dimethyl-1-(1-oxoethyl)indoline hydrochloride; 1-(6-Amino-3,3-dimethylindolin-1-yl)ethanone HCl; N-Acetyl-6-amino-3,3-dimethylindoline hydrochloride; 2,3-Dihydro-6-amino-3,3-dimethyl-1H-indol-1-yl ethyl ketone hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(6-Amino-3,3-Dimethylindolin-1-Yl)Ethanone Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.