Description

2-Bromo-4-Fluoro-3-Hydroxytolulene is a halogenated aromatic compound that serves as a versatile and valuable synthetic intermediate. Its molecular structure, featuring bromine, fluorine, and hydroxyl substituents on a toluene backbone, makes it a critical building block for the development of more complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries. Its controlled reactivity allows for selective functionalization, enabling the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic motifs.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and pesticides, where the fluorine and bromine atoms can enhance biological activity and stability.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials due to its tunable electronic properties.
• Organic Synthesis & Catalysis: Serves as a substrate in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other metal-catalyzed transformations to create complex molecular architectures.
• Dye and Pigment Manufacturing: Intermediate for synthesizing halogenated dyes and pigments, where it can influence color fastness and spectral properties.

Basic Information

Product Name	2-Bromo-4-Fluoro-3-Hydroxytolulene
CAS No.	1226808-63-4
Molecular Formula	C7H6BrFO
Molecular Weight	205.03 g/mol
Synonyms	3-Hydroxy-2-bromo-4-fluorotoluene; 2-Bromo-4-fluoro-3-methylphenol; 4-Fluoro-2-bromo-3-methylphenol; 3-Methyl-6-bromo-4-fluorophenol; Toluene, 2-bromo-4-fluoro-3-hydroxy-; 2-Bromo-4-fluoro-m-cresol
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Fluoro-3-Hydroxytolulene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We are committed to meeting the stringent requirements of cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.