Description

1,2,3,9-Tetrahydro-9-(Methyl-D3)-4H-Carbazol-4-One is a deuterated analog of a key carbazole derivative, featuring a trideuterated methyl group for enhanced metabolic stability and traceability in research applications. This compound is valued for its role as a sophisticated intermediate in the development of novel pharmaceuticals and advanced materials. It is primarily sought by research institutions and pharmaceutical companies engaged in drug discovery, metabolic studies, and the synthesis of labeled compounds for analytical standards.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of deuterated drug candidates, leveraging the kinetic isotope effect for improved metabolic profiles.
• Metabolic Research: Used as a stable isotope-labeled internal standard in LC-MS and GC-MS for accurate quantification and metabolite tracking in pharmacokinetic studies.
• Analytical Reference Standard: Serves as a high-purity certified reference material (CRM) for method development and validation in analytical laboratories.
• Organic Electronics Research: Acts as a precursor for developing novel carbazole-based materials with potential applications in OLEDs and photoconductors.
• Chemical Biology Probes: Utilized in the creation of tagged molecular probes for studying biological pathways and protein interactions.

Basic Information

Item	Details
Product Name	1,2,3,9-Tetrahydro-9-(Methyl-D3)-4H-Carbazol-4-One
CAS No.	1225443-54-8
Molecular Formula	C13H10D3NO
Molecular Weight	202.27 g/mol
Synonyms	9-(Methyl-d3)-1,2,3,9-tetrahydro-4H-carbazol-4-one; 1,2,3,9-Tetrahydro-9-(trideuteriomethyl)-4H-carbazol-4-one; Carbazol-4-one, 1,2,3,9-tetrahydro-9-(methyl-d3)-; Deuterated Carbazole Ketone; (Methyl-D3)-Carbazolone; Tetrahydrocarbazolone-d3
EINECS	Contact for details

Quality Control

Every batch of 1,2,3,9-Tetrahydro-9-(Methyl-D3)-4H-Carbazol-4-One is manufactured under a strict quality management system. We provide comprehensive analytical data to support research and development requirements, including confirmation of isotopic purity and chemical identity. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting key parameters such as chemical purity, isotopic enrichment, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D3, by NMR)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.