Description

1H-Pyrazolo[4,3-C]Isoquinoline-3-Carboxamide,4,5-Dihydro-1-Methyl-n-(6-Methyl-2-Pyridinyl)-5-Oxo- is a high-purity, advanced pharmaceutical intermediate belonging to the fused heterocyclic compound class. This compound is valued for its role as a critical building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry research and development. It is primarily sought by R&D laboratories and pharmaceutical manufacturers focused on developing new therapeutic agents, especially in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Kinase Inhibitor Development: Serves as a building block for potential kinase inhibitors, a major class of targeted cancer therapies.
• CNS Drug Discovery: Employed in the synthesis of compounds targeting neurological pathways and receptors.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for exploratory chemistry and pharmacological studies.

Basic Information

Item	Details
Product Name	1H-Pyrazolo[4,3-C]Isoquinoline-3-Carboxamide,4,5-Dihydro-1-Methyl-n-(6-Methyl-2-Pyridinyl)-5-Oxo-
CAS No.	1225376-86-2
Molecular Formula	C18H17N5O2
Molecular Weight	335.36 g/mol
Synonyms	4,5-Dihydro-1-methyl-N-(6-methyl-2-pyridinyl)-5-oxo-1H-pyrazolo[4,3-c]isoquinoline-3-carboxamide; 1-Methyl-4,5-dihydro-5-oxo-N-(6-methyl-2-pyridinyl)-1H-pyrazolo[4,3-c]isoquinoline-3-carboxamide; UNII-8P3Q6U4W1F; 8P3Q6U4W1F; 1H-Pyrazolo[4,3-c]isoquinoline-3-carboxamide, 4,5-dihydro-1-methyl-N-(6-methyl-2-pyridinyl)-5-oxo-; BDBM50192385; HY-101077; AKOS025147064
EINECS	Contact for details

Quality Control

Our 1H-Pyrazolo[4,3-C]Isoquinoline-3-Carboxamide,4,5-Dihydro-1-Methyl-n-(6-Methyl-2-Pyridinyl)-5-Oxo- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere if long-term storage is required to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.