Description

3-(2-Chloro-10H-Phenothiazin-10-Yl)-N,n-Bis(Methyl-D3)Propan-1-Amine is a deuterated derivative of a phenothiazine-based compound, specifically designed for advanced research and development applications. This compound is critical for studies requiring isotopic labeling, such as in pharmacokinetics, metabolic pathway tracing, and analytical method development. It is primarily utilized by pharmaceutical researchers, contract research organizations (CROs), and academic institutions engaged in the development of novel therapeutics and diagnostic agents.

Application

• Isotopic Internal Standard for the precise quantification of its non-deuterated counterpart in bioanalytical methods using LC-MS/MS.
• Metabolic Studies and tracer research to investigate drug metabolism, distribution, and excretion (DMPK) in preclinical models.
• Pharmaceutical Reference Standard for quality control and method validation in the synthesis of deuterated drug candidates.
• Chemical Biology Research as a tool compound for probing biological mechanisms and protein interactions where isotopic labeling is required.
• Stable Isotope Labeling in the development of new chemical entities (NCEs) for improved pharmacokinetic profiles.

Basic Information

Product Name	3-(2-Chloro-10H-Phenothiazin-10-Yl)-N,n-Bis(Methyl-D3)Propan-1-Amine
CAS No.	1224691-01-3
Molecular Formula	C₁₉H₁₇D₆ClN₂S
Molecular Weight	Contact for details
Synonyms	N,N-Bis(methyl-d3)-3-(2-chloro-10H-phenothiazin-10-yl)propan-1-amine; 2-Chloro-N,N-bis(trideuteriomethyl)-10H-phenothiazine-10-propanamine; Deuterated Chlorpromazine Metabolite Standard; d6-Chlorpromazine Derivative; 3-(2-Chloro-phenothiazin-10-yl)-N,N-bis(methyl-d3)propylamine; (2-Chloro-10H-phenothiazin-10-yl)-N,N-bis(trideuteriomethyl)propan-1-amine
EINECS	Contact for details

Quality Control

Our high-purity deuterated compounds are manufactured under strict quality control protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity (by HPLC/NMR), isotopic enrichment, and other critical parameters. We adhere to relevant standards for research chemicals, and custom synthesis and purification services are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99.0 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.