Description

1-(4-Acetylpiperazin-1-Yl)-2-(4-Bromo-1H-Indol-1-Yl)Ethanone is a high-purity, advanced pharmaceutical intermediate designed for research and development in medicinal chemistry. This compound is valued for its role as a key synthetic building block in the creation of novel bioactive molecules, particularly those targeting central nervous system (CNS) disorders and oncological pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, especially for neurological and psychiatric targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new therapeutic agents.
• Biochemical Tool Compound: Acts as a research chemical for probing biological pathways and enzyme interactions in vitro.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up synthesis under cGMP conditions.
• Academic Research: Employed in university laboratories for advanced organic synthesis projects and pharmacological studies.
• Library Synthesis: A valuable scaffold for generating diverse chemical libraries for high-throughput screening (HTS) campaigns.

Basic Information

Product Name	1-(4-Acetylpiperazin-1-Yl)-2-(4-Bromo-1H-Indol-1-Yl)Ethanone
CAS No.	1224170-03-9
Molecular Formula	C₁₆H₁₈BrN₃O₂
Molecular Weight	364.24 g/mol
Synonyms	1-(4-Acetylpiperazin-1-yl)-2-(4-bromo-1H-indol-1-yl)ethanone; 2-(4-Bromo-1H-indol-1-yl)-1-(4-acetylpiperazin-1-yl)ethanone; 4-Bromo-1-[2-(4-acetyl-1-piperazinyl)-2-oxoethyl]-1H-indole; 1224170-03-9; 4-Bromo-1-(2-(4-acetylpiperazin-1-yl)-2-oxoethyl)-1H-indole; Ethanone, 1-(4-acetyl-1-piperazinyl)-2-(4-bromo-1H-indol-1-yl)-
EINECS	Contact for details

Quality Control

Our 1-(4-Acetylpiperazin-1-Yl)-2-(4-Bromo-1H-Indol-1-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to ISO 9001 standards, and we can support development projects requiring material produced under cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.