Description

2-(Dimethoxymethyl)-6-Fluoro-1,8-Naphthyridine is a high-purity, advanced pharmaceutical intermediate characterized by its unique naphthyridine core functionalized with fluorine and a dimethoxymethyl group. This compound is of significant commercial value for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting kinase inhibition or other biological pathways where the 1,8-naphthyridine moiety is pharmacologically active.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, or insecticides, leveraging the biological activity of fluorinated naphthyridine derivatives.
• Material Science: Potential use in the development of organic electronic materials or ligands for catalytic systems due to its electron-deficient aromatic structure.
• Chemical Synthesis: Used in academic and industrial R&D for constructing more complex molecular architectures via further functionalization of the reactive dimethoxymethyl group.

Basic Information

Product Name	2-(Dimethoxymethyl)-6-Fluoro-1,8-Naphthyridine
CAS No.	1222533-72-3
Molecular Formula	C₁₁H₁₁FN₂O₂
Molecular Weight	222.22 g/mol
Synonyms	6-Fluoro-2-(dimethoxymethyl)-1,8-naphthyridine; 2-(Dimethoxymethyl)-6-fluoro-1,8-naphthyridine; 1,8-Naphthyridine, 6-fluoro-2-(dimethoxymethyl)-; CAS 1222533-72-3
EINECS	Contact for details

Quality Control

Our 2-(Dimethoxymethyl)-6-Fluoro-1,8-Naphthyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for critical R&D and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.