Description

8-Bromo-5-Fluoroisoquinolin-3-Amine is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique halogenated isoquinoline scaffold makes it a critical intermediate for the development of novel pharmacologically active compounds. This product is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for creating new molecular entities targeting a range of diseases and applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small molecule drug candidates, particularly in oncology and CNS research.
• Agrochemical Development: Used to construct novel active ingredients for crop protection products, leveraging its halogenated structure.
• Material Science Research: Serves as a building block for creating organic electronic materials and specialty polymers.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Library Synthesis for HTS: A valuable scaffold for generating diverse compound libraries used in high-throughput screening (HTS) campaigns.
• Fluorescent Dye & Sensor Development: The amine and halogen functional groups allow for derivatization into advanced fluorophores and chemosensors.

Basic Information

Item	Details
Product Name	8-Bromo-5-Fluoroisoquinolin-3-Amine
CAS No.	1221974-48-6
Molecular Formula	C9H6BrFN2
Molecular Weight	241.06 g/mol
Synonyms	3-Amino-8-bromo-5-fluoroisoquinoline; 8-Bromo-5-fluoro-3-isoquinolinamine; 8-Bromo-5-fluoro-isoquinolin-3-ylamine; 5-Fluoro-8-bromoisoquinolin-3-amine; 1221974-48-6; 8-Br-5-F-IQ-3-NH2; 3-Amino-8-bromo-5-fluoroisoquinoline
EINECS	Contact for details

Quality Control

Our 8-Bromo-5-Fluoroisoquinolin-3-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.