Description

5-Fluoroisoquinolin-3-Amine CAS NO 1221974-43-1 is a high-purity fluorinated isoquinoline derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a fluorine atom and an amine group on the isoquinoline scaffold, makes it a valuable intermediate for creating novel compounds with targeted biological activity. This chemical is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on medicinal chemistry and the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in oncology, CNS disorders, and anti-infective therapies.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Chemical Biology Probe: Serves as a scaffold for developing molecular probes to study enzyme function and biological pathways.
• Material Science Precursor: Potential intermediate in the synthesis of advanced organic materials, such as ligands for catalysts or components for organic electronics.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploration of new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	5-Fluoroisoquinolin-3-Amine
CAS No.	1221974-43-1
Molecular Formula	C9H7FN2
Molecular Weight	162.16 g/mol
Synonyms	3-Amino-5-fluoroisoquinoline; 5-Fluoro-3-isoquinolinamine; 5-Fluoro-isoquinolin-3-ylamine; 5-Fluoroisoquinolin-3-amine; 1221974-43-1; 5-Fluoro-3-aminoisoquinoline
EINECS	Contact for details

Quality Control

Our 5-Fluoroisoquinolin-3-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if possible to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.