Description

5-Chloroisoquinolin-3-Amine is a high-purity organic building block with the CAS registry number 1221974-27-1. This compound is a versatile intermediate of significant value in modern synthetic chemistry, particularly for constructing complex nitrogen-containing heterocycles. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a precursor for organic ligands in catalysis and for the synthesis of functional polymers and dyes.
• Academic & R&D: Essential for methodological studies in organic synthesis, including cross-coupling reactions and heterocycle functionalization.
• Chemical Biology: Employed as a scaffold or probe in the design of molecules for studying biological pathways and protein interactions.

Basic Information

Product Name	5-Chloroisoquinolin-3-Amine
CAS No.	1221974-27-1
Molecular Formula	C9H7ClN2
Molecular Weight	178.62 g/mol
Synonyms	3-Amino-5-chloroisoquinoline; 5-Chloro-3-isoquinolinamine; 5-Chloroisoquinolin-3-ylamine; 1221974-27-1; 5-Chloro-3-aminoisoquinoline; 3-Isoquinolinamine, 5-chloro-; 5-Chloro-3-isoquinolinamine
EINECS	Contact for details

Quality Control

Every batch of 5-Chloroisoquinolin-3-Amine is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development. A detailed Certificate of Analysis (COA), confirming identity, purity, and impurity profiles via techniques such as HPLC, NMR, and MS, is supplied with each shipment to guarantee reproducible results for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.