Description

D6-6,7-Dimethoxy-3,4-Dihydroisoquinoline is a deuterated derivative of a key isoquinoline scaffold, offering enhanced metabolic stability for advanced research and development. This compound serves as a critical building block and stable isotope-labeled intermediate in the synthesis of complex pharmaceutical molecules. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries for drug discovery, metabolic studies, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Acts as a deuterium-labeled precursor in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Metabolic Pathway Tracing: Used in pharmacokinetic and metabolism studies (ADME) due to its deuterium labeling, allowing for precise tracking within biological systems.
• Isotope Dilution Mass Spectrometry: Serves as an internal standard for the accurate quantitative analysis of related compounds in complex matrices.
• Medicinal Chemistry Research: Provides a versatile scaffold for structure-activity relationship (SAR) studies and the development of novel bioactive molecules.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce the dihydroisoquinoline moiety into more complex molecular architectures.
• Agrochemical Development: Used in the research and synthesis of new active ingredients for crop protection.

Basic Information

Item	Details
Product Name	D6-6,7-Dimethoxy-3,4-Dihydroisoquinoline
CAS No.	1221885-61-5
Molecular Formula	C11H7D6NO2
Molecular Weight	~197.26 g/mol
Synonyms	6,7-Dimethoxy-3,4-dihydroisoquinoline-d6; Deuterated 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline; 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-d6; 6,7-Dimethoxy-3,4-dihydroisoquinoline (hexadeuterated); D6-6,7-Dimethoxy-THIQ; 6,7-Dimethoxy-3,4-dihydroisoquinoline (D6); (3,4-Dihydro-6,7-dimethoxyisoquinoline)-d6; 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline (hexadeuterated)
EINECS	Contact for details

Quality Control

Our D6-6,7-Dimethoxy-3,4-Dihydroisoquinoline is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C) for structural and isotopic purity confirmation and HPLC for chemical purity assessment. Certificates of Analysis (COA) detailing isotopic enrichment (D%), chemical purity, and identity are available upon request to ensure compliance with your specific research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container sealed under an inert atmosphere if possible to maximize long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Purity (D%)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.