Description

5-(Trifluoromethyl)-1H-Indole-7-Carbonitrile is a high-value, multi-functional indole derivative characterized by its trifluoromethyl and nitrile functional groups. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in oncology, CNS disorders, and anti-inflammatory therapies.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the biological activity of the indole scaffold and fluorine atoms.
• Material Science Precursor: Serves as a building block for organic electronic materials, liquid crystals, and advanced polymers due to its electron-withdrawing groups.
• Chemical Synthesis: Employed in cross-coupling reactions, cyclizations, and as a precursor for further functionalization to create diverse chemical libraries.
• Academic & Industrial R&D: Essential for medicinal chemistry programs and process chemistry development in contract research and manufacturing organizations (CROs/CMOs).

Basic Information

Product Name	5-(Trifluoromethyl)-1H-Indole-7-Carbonitrile
CAS No.	1221792-90-0
Molecular Formula	C10H5F3N2
Molecular Weight	210.16 g/mol
Synonyms	7-Cyano-5-(trifluoromethyl)-1H-indole; 5-(Trifluoromethyl)-7-cyanoindole; 1H-Indole-7-carbonitrile, 5-(trifluoromethyl)-; 1221792-90-0; 5-Trifluoromethyl-1H-indole-7-carbonitrile
EINECS	Contact for details

Quality Control

Our production of 5-(Trifluoromethyl)-1H-Indole-7-Carbonitrile adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.