Description

1-(3-Bromo-2-Fluorophenyl)Ethanol is a versatile fluorinated and brominated aromatic alcohol building block. This compound is highly valued in advanced organic synthesis for its dual halogen functionality, which allows for selective and sequential chemical transformations. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) and anti-inflammatory agents.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, and insecticides, leveraging the fluorine and bromine atoms for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Used to construct sophisticated chiral ligands for asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Material Science Research: Employed in the synthesis of specialty monomers for advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Acts as a building block for fluorescent tags, molecular probes, and other tools used in biochemical and diagnostic research.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales, from laboratory to pilot plant.

Basic Information

Product Name	1-(3-Bromo-2-Fluorophenyl)Ethanol
CAS No.	1221715-80-5
Molecular Formula	C8H8BrFO
Molecular Weight	219.05 g/mol
Synonyms	(3-Bromo-2-fluorophenyl)methanol; 1-(3-Bromo-2-fluorophenyl)methanol; 3-Bromo-2-fluorobenzyl alcohol; (3-Bromo-2-fluorophenyl)carbinol; α-Hydroxymethyl-3-bromo-2-fluorobenzene; 2-Fluoro-3-bromobenzyl alcohol; NSC 876841
EINECS	Contact for details

Quality Control

Our production of 1-(3-Bromo-2-Fluorophenyl)Ethanol adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment. Our facilities operate under cGMP principles suitable for pharmaceutical intermediate manufacturing, ensuring reliable supply and batch-to-batch reproducibility for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and potential degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.