Description

Ethyl 2-Bromo-6-Formyl-4H-Thieno[3,2-B]Pyrrole-5-Carboxylate is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both bromo and formyl substituents on a fused thienopyrrole core, makes it a versatile precursor for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, anti-cancer agents, and central nervous system (CNS) active compounds.
• Agrochemical Research: Serves as a crucial building block for developing new generations of herbicides, fungicides, and insecticides with novel modes of action.
• Material Science Precursor: Used in the research and development of organic semiconductors, conductive polymers, and non-linear optical (NLO) materials due to its electron-rich heterocyclic structure.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic & Institutional Research: A valuable reagent for universities and research institutes exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	Ethyl 2-Bromo-6-Formyl-4H-Thieno[3,2-B]Pyrrole-5-Carboxylate
CAS No.	1221186-54-4
Molecular Formula	C10H8BrNO3S
Molecular Weight	302.14 g/mol
Synonyms	Ethyl 2-bromo-6-formyl-4H-thieno[3,2-b]pyrrole-5-carboxylate; 5-Carbethoxy-2-bromo-6-formyl-4H-thieno[3,2-b]pyrrole; 2-Bromo-6-formyl-4H-thieno[3,2-b]pyrrole-5-carboxylic acid ethyl ester; 4H-Thieno[3,2-b]pyrrole-5-carboxylic acid, 2-bromo-6-formyl-, ethyl ester; Ethyl 2-bromo-6-formyl-4H-thieno[3,2-b]pyrrole-5-carboxylate (CAS 1221186-54-4)
EINECS	Contact for details

Quality Control

Every batch of Ethyl 2-Bromo-6-Formyl-4H-Thieno[3,2-B]Pyrrole-5-Carboxylate is manufactured under strict quality management systems and undergoes comprehensive analytical characterization. Our products are tested to ensure they meet the high-purity standards required for research and process development. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles via techniques such as HPLC, NMR, and MS.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Maximum Impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.