Description

1-Ethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indazole is a high-value boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. This advanced intermediate is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries developing novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates, particularly in creating biaryl and heterobiaryl structures common in active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science: Serves as a monomer or precursor in the synthesis of organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Chemical Biology & Probe Development: Employed in creating molecular probes and labeled compounds for biochemical assays and diagnostic research.
• Academic & Contract Research: A vital reagent for methodology development and complex molecule synthesis in academic laboratories and CROs/CDMOs.
• Ligand Synthesis: Precursor for creating sophisticated ligands used in catalysis and coordination chemistry.

Basic Information

Product Name	1-Ethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indazole
CAS No.	1220696-51-4
Molecular Formula	C15H21BN2O2
Molecular Weight	272.15 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-ethyl-1H-indazole; 1-Ethyl-1H-indazole-5-boronic acid pinacol ester; 1-Ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole; 1-Ethyl-5-(pinacolboronato)indazole; 1-Ethyl-5-indazoleboronic acid pinacol ester; 5-Borono-1-ethyl-1H-indazole pinacol ester; 1220696-51-4
EINECS	Contact for details

Quality Control

Our 1-Ethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.