Description

2-[(3,5-Dimethyl-1,2-Oxazol-4-Yl)Sulfonyl]-1-Methyloctahydroisoquinolin-4A(2H)-Ol is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure incorporating an isoquinoline core and a sulfonyl-substituted oxazole moiety. This compound is of significant value in modern organic synthesis, particularly for the development of novel active pharmaceutical ingredients (APIs) with targeted biological activity. It is primarily required by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of new chemical entities for therapeutic applications.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potential drug candidates, especially those targeting the central nervous system (CNS) or other specialized receptors.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new molecules with improved efficacy and safety profiles.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and development services for the global pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for exploring new synthetic methodologies and heterocyclic chemistry.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	2-[(3,5-Dimethyl-1,2-Oxazol-4-Yl)Sulfonyl]-1-Methyloctahydroisoquinolin-4A(2H)-Ol
CAS No.	1220108-77-9
Molecular Formula	C₁₇H₂₆N₂O₄S
Molecular Weight	354.47 g/mol
Synonyms	1-Methyl-2-[(3,5-dimethyl-4-isoxazolyl)sulfonyl]decahydro-4a-isoquinolinol; 1-Methyl-2-((3,5-dimethylisoxazol-4-yl)sulfonyl)decahydroisoquinolin-4a-ol; 4a-Hydroxy-1-methyl-2-((3,5-dimethylisoxazol-4-yl)sulfonyl)decahydroisoquinoline; 2-((3,5-Dimethylisoxazol-4-yl)sulfonyl)-1-methyloctahydro-4a(2H)-isoquinolinol; Advanced Pharmaceutical Intermediate 1220108-77-9; Isoxazole-sulfonyl isoquinoline derivative.
EINECS	Contact for details

Quality Control

Our production of 2-[(3,5-Dimethyl-1,2-Oxazol-4-Yl)Sulfonyl]-1-Methyloctahydroisoquinolin-4A(2H)-Ol adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided for each lot, and we support audits and regulatory documentation as needed.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary to prevent moisture uptake and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 10 ppm
Assay	97.0% - 102.0% (on anhydrous basis)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.