Description

5-Bromo-1H-Indazole-7-Carboxylic Acid Ethyl Ester is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. Its core value lies in its functionalized indazole scaffold, which serves as a critical precursor in the development of novel pharmacologically active compounds. This intermediate is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of kinase inhibitors and other targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its modifiable bromo and ester functional groups.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new crop protection agents and pesticides.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying enzyme function and biological pathways.
• Material Science: Potential use in the synthesis of specialty polymers and advanced organic materials with specific electronic properties.

Basic Information

Product Name	5-Bromo-1H-Indazole-7-Carboxylic Acid Ethyl Ester
CAS No.	1220039-34-8
Molecular Formula	C10H9BrN2O2
Molecular Weight	269.10 g/mol
Synonyms	Ethyl 5-Bromo-1H-indazole-7-carboxylate; 5-Bromo-1H-indazole-7-carboxylic acid ethyl ester; 7-(Ethoxycarbonyl)-5-bromo-1H-indazole; 5-Bromo-7-(ethoxycarbonyl)-1H-indazole; 1H-Indazole-7-carboxylic acid, 5-bromo-, ethyl ester; 1220039-34-8
EINECS	Contact for details

Quality Control

Our 5-Bromo-1H-Indazole-7-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.