Description

2-(2-Pyrrolidinylmethyl)-1,2,3,4-Tetrahydroisoquinoline Dihydrochloride is a high-purity, synthetic organic compound supplied as a dihydrochloride salt. This specialized chemical is valued for its role as a critical intermediate or building block in advanced pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs) and other complex molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel therapeutic compounds and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in drug discovery programs for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry Development: Serves as a critical starting material or intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Biochemical Research: Potential use as a ligand or precursor in the development of biochemical probes and tools for studying biological systems.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services.

Basic Information

Product Name	2-(2-Pyrrolidinylmethyl)-1,2,3,4-Tetrahydroisoquinoline Dihydrochloride
CAS No.	1220019-41-9
Molecular Formula	C14H20N2 • 2HCl
Molecular Weight	289.24 g/mol (free base: 216.32 g/mol)
Synonyms	1,2,3,4-Tetrahydro-2-[(2-pyrrolidinyl)methyl]isoquinoline dihydrochloride; 2-(Pyrrolidin-2-ylmethyl)-1,2,3,4-tetrahydroisoquinoline dihydrochloride; THIQ-Pyrrolidine Dihydrochloride; 1220019-41-9; 2-(2-Pyrrolidinylmethyl)-1,2,3,4-tetrahydroisoquinoline HCl
EINECS	Contact for details

Quality Control

Every batch of 2-(2-Pyrrolidinylmethyl)-1,2,3,4-Tetrahydroisoquinoline Dihydrochloride is manufactured and tested under stringent quality management systems. We provide comprehensive analytical data to support research and development applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed specifications from HPLC, NMR, and other analytical techniques are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.