Description

2-(3-Pyrrolidinyl)-1,2,3,4-Tetrahydroisoquinolinedihydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 1220017-74-2. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents targeting the central nervous system. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of complex, bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery.
• Biochemical Research: Serves as a tool compound for investigating biological pathways and receptor interactions.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value organic molecules for various applications.
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	2-(3-Pyrrolidinyl)-1,2,3,4-Tetrahydroisoquinolinedihydrochloride
CAS No.	1220017-74-2
Molecular Formula	C₁₃H₁₈N₂·2HCl
Molecular Weight	279.21 g/mol (Free base: 202.30 g/mol)
Synonyms	2-(Pyrrolidin-3-yl)-1,2,3,4-tetrahydroisoquinoline dihydrochloride; 1,2,3,4-Tetrahydro-2-(3-pyrrolidinyl)isoquinoline dihydrochloride; 2-(3-Pyrrolidinyl)-1,2,3,4-tetrahydroisoquinoline HCl; Pyrrolidinyltetrahydroisoquinoline dihydrochloride; 1220017-74-2; PTIQ·2HCl
EINECS	Contact for details

Quality Control

Our 2-(3-Pyrrolidinyl)-1,2,3,4-Tetrahydroisoquinolinedihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.