Description

2-Formyl-4-(Trifluoromethyl)Phenylboronic Acid Pinacol Ester is a high-value, multifunctional organoboron building block essential for modern synthetic chemistry. Its core value lies in the strategic combination of a formyl group and a protected boronic acid moiety on a trifluoromethylated aromatic ring, enabling efficient cross-coupling and subsequent functionalization in a single molecule. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used to create advanced active ingredients with enhanced biological activity and environmental stability, leveraging the trifluoromethyl group.
• Liquid Crystal & OLED Material Development: Serves as a building block for constructing complex, fluorinated organic molecules used in electronic displays and lighting.
• Metal-Organic Framework (MOF) Construction: Employed as a linker molecule to create porous materials with tailored properties for gas storage and catalysis.
• Fluorine-Containing Polymer Research: Acts as a monomer or co-monomer for developing specialty polymers with unique surface, thermal, and chemical resistance properties.
• Chemical Biology & Probe Development: Utilized in the synthesis of bioconjugates and molecular probes for studying biological processes.

Basic Information

Product Name	2-Formyl-4-(Trifluoromethyl)Phenylboronic Acid Pinacol Ester
CAS No.	1219936-17-0
Molecular Formula	C14H16BF3O3
Molecular Weight	300.09 g/mol
Synonyms	4-Formyl-2-(Trifluoromethyl)Benzeneboronic Acid Pinacol Ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)benzaldehyde; 5-(Trifluoromethyl)-2-formylphenylboronic Acid Pinacol Ester; (2-Formyl-4-(trifluoromethyl)phenyl)boronic Acid Pinacol Ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-α,α,α-trifluoro-p-tolualdehyde; Pinacol [2-Formyl-4-(trifluoromethyl)phenyl]boronate
EINECS	Contact for details

Quality Control

Our 2-Formyl-4-(Trifluoromethyl)Phenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for demanding research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere. This material is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.