Description

4-[3-(1,1,1,2,3,3,3-Heptadeuteriopropan-2-Ylamino)-2-Hydroxypropoxy]Naphthalen-1-Ol is a deuterated derivative of a naphthalenol-based compound, designed for advanced research and development applications where isotopic labeling is critical. This high-purity compound is essential for studies in pharmacokinetics, metabolic pathway tracing, and as an internal standard in quantitative mass spectrometry. It is primarily utilized by pharmaceutical R&D laboratories, analytical service providers, and academic institutions focused on drug discovery and development.

Application

• Internal Standard for LC-MS/MS: Used as a stable, isotopically labeled internal standard for the precise quantification of its non-deuterated counterpart in bioanalytical methods.
• Metabolic Studies: Employed in drug metabolism and pharmacokinetics (DMPK) research to trace and identify metabolites, leveraging the deuterium atoms as tracers.
• Pharmaceutical R&D: Serves as a key intermediate or reference material in the development and validation of novel therapeutic agents.
• Isotope Dilution Analysis: Critical for high-accuracy analytical techniques requiring isotope dilution to correct for matrix effects and instrument variability.
• Biochemical Research: Used in mechanistic studies to investigate enzyme activity, receptor binding, and other biochemical pathways.
• Quality Control Reference: Acts as a certified reference material (CRM) for ensuring the accuracy and reliability of analytical results in regulated environments.

Basic Information

Item	Detail
Product Name	4-[3-(1,1,1,2,3,3,3-Heptadeuteriopropan-2-Ylamino)-2-Hydroxypropoxy]Naphthalen-1-Ol
CAS No.	1219908-86-7
Molecular Formula	C₁₆H₁₆D₇NO₃
Molecular Weight	Contact for details
Synonyms	1-Naphthol, 4-[3-[(1,1,1,2,3,3,3-heptadeuterio-2-propanyl)amino]-2-hydroxypropoxy]-; 4-[3-[(Heptadeuterioisopropyl)amino]-2-hydroxypropoxy]-1-naphthol; Deuterated Carvedilol Metabolite Standard; (Heptadeuteriopropan-2-yl)[2-hydroxy-3-(1-hydroxynaphthalen-4-yloxy)propyl]amine-d7; Isotopically Labeled Naphthalenol Derivative; D7-Labeled Adrenergic Blocker Analog; 4-(3-((1,1,1,2,3,3,3-Heptadeuterio-2-propyl)amino)-2-hydroxypropoxy)-1-naphthalenol
EINECS	Contact for details

Quality Control

Our 4-[3-(1,1,1,2,3,3,3-Heptadeuteriopropan-2-Ylamino)-2-Hydroxypropoxy]Naphthalen-1-Ol is manufactured under strict quality systems to ensure the high isotopic purity and chemical integrity required for sensitive analytical applications. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR and HPLC-MS, to confirm identity, isotopic enrichment, and chemical purity. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.