Description

3,4,5-Trimethoxybenzyl-D9 Alcohol is a deuterium-labeled derivative of 3,4,5-trimethoxybenzyl alcohol, a key synthetic intermediate and building block. This compound is specifically valued for its use as an internal standard in quantitative mass spectrometry, enabling precise and accurate analysis in complex matrices. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors who require high-fidelity isotopic labeling for method development, metabolic studies, and quality control.

Application

• Internal Standard for LC-MS/MS: Primary application as a stable, isotopically labeled internal standard for the quantitative analysis of its non-deuterated counterpart or related compounds in bioanalytical and pharmacokinetic studies.
• Pharmaceutical Research: Critical intermediate in the synthesis of deuterated drug candidates and active pharmaceutical ingredients (APIs) for metabolic stability and tracing studies.
• Metabolite Identification: Used in drug metabolism and pharmacokinetics (DMPK) research to track and identify metabolites, improving the understanding of drug pathways.
• Analytical Reference Standard: Serves as a certified reference material (CRM) for calibrating analytical instruments and validating testing methods in quality control laboratories.
• Chemical Synthesis Building Block: Acts as a versatile precursor for synthesizing more complex deuterated molecules in medicinal chemistry and material science.
• Agrochemical Development: Employed in the research and development of labeled agrochemicals for environmental fate and residue analysis studies.

Basic Information

Product Name	3,4,5-Trimethoxybenzyl-D9 Alcohol
CAS No.	1219805-74-9
Molecular Formula	C11H7D9O4
Molecular Weight	215.29 g/mol (for D9 isotopologue)
Synonyms	(3,4,5-Trimethoxyphenyl)methan-d9-ol; Benzyl-d9 Alcohol, 3,4,5-Trimethoxy-; 3,4,5-Trimethoxybenzyl Alcohol-d9; 3,4,5-Trimethoxy(d9)benzyl Alcohol; Deuterated 3,4,5-Trimethoxybenzyl Alcohol; 3,4,5-TMBA-d9; 3,4,5-TMPM-d9; 3,4,5-Trimethoxybenzyl-α,α,α,2,3,4,5,6,6-d9 Alcohol
EINECS	Contact for details

Quality Control

Our 3,4,5-Trimethoxybenzyl-D9 Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C), mass spectrometry, and HPLC, to confirm chemical identity, isotopic purity (D-enrichment ≥ 98 atom % D), and chemical purity. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to ensure full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light). For long-term storage under inert atmosphere is recommended to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98 atom % D
Chemical Purity (NMR)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.