Description

Diethyl-2,2,2,2′,2′,2′-D6-Amine Hcl is a deuterium-labeled isotopologue of diethylamine hydrochloride, a valuable building block for advanced chemical synthesis and analytical applications. This compound is specifically engineered to provide a stable, non-radioactive isotopic label, making it a critical tool for mechanistic studies, metabolic pathway tracing, and internal standard preparation in mass spectrometry. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and analytical chemistry sectors who require high-fidelity isotopic markers for their development and quality control workflows.

Application

• Pharmaceutical Research & Development: Serves as a deuterated precursor or intermediate in the synthesis of isotopically labeled active pharmaceutical ingredients (APIs) for drug metabolism and pharmacokinetics (DMPK) studies.
• Analytical Chemistry: Used as a stable isotope-labeled internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the accurate quantification of diethylamine and related compounds.
• Mechanistic Studies: Enables the tracing of reaction pathways and the study of kinetic isotope effects (KIE) in organic and catalytic chemistry research.
• Agrochemical Development: Employed in the synthesis of labeled pesticide or herbicide analogs for environmental fate and metabolism studies.
• Material Science: Acts as a specialty reagent or modifying agent in the development of novel polymers or surface coatings where isotopic purity is required.
• Nuclear Magnetic Resonance (NMR) Spectroscopy: Useful as a deuterated solvent additive or a probe molecule in NMR analysis due to its distinct spectral properties.

Basic Information

Product Name	Diethyl-2,2,2,2′,2′,2′-D6-Amine Hcl
CAS No.	1219805-68-1
Molecular Formula	C4H5D6ClN
Molecular Weight	113.64 g/mol
Synonyms	Diethylamine-d11 hydrochloride; Perdeuterated Diethylamine Hydrochloride; (C2D5)2NH•HCl; N,N-Diethyl-d10-amine hydrochloride; Deuterated Diethylamine HCl; Diethylamine-d11 HCl; Diethylamine (hexadeutero) hydrochloride; N-Ethyl-N-(ethyl-d5)amine hydrochloride
EINECS	Contact for details

Quality Control

Our Diethyl-2,2,2,2′,2′,2′-D6-Amine Hcl is produced under controlled conditions to ensure high isotopic and chemical purity, meeting the stringent requirements of research and development. Each batch undergoes rigorous analytical testing, including NMR (¹H, ²H, ¹³C) and mass spectrometry, to confirm isotopic enrichment and chemical identity. Certificates of Analysis (COA) detailing purity, isotopic abundance, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption, which can affect product stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (²H NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.