Description

3-Aminopyridine-D6 is a deuterium-labeled isotopologue of 3-aminopyridine, a key building block in organic synthesis and analytical chemistry. This high-purity labeled compound is essential for creating internal standards in mass spectrometry, enabling precise quantification and metabolic pathway tracing in complex biological matrices. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and life science sectors for drug development, metabolite identification, and advanced analytical method validation.

Application

• Internal Standard for LC-MS/MS: Serves as a critical, non-interfering reference standard for the accurate quantification of 3-aminopyridine and related compounds in bioanalytical studies.
• Metabolic Pathway Tracing: Used in pharmacokinetic and drug metabolism research to track the fate of drug molecules and identify metabolites using deuterium as a stable isotopic tracer.
• Pharmaceutical Intermediate: Acts as a deuterated synthon in the synthesis of labeled active pharmaceutical ingredients (APIs) for clinical trials and regulatory studies.
• Analytical Reference Material: Provides a certified reference material for method development, validation, and quality control in analytical laboratories.
• Isotope Dilution Mass Spectrometry (IDMS): Essential for high-accuracy measurements in environmental testing, food safety analysis, and clinical diagnostics.
• NMR Solvent & Reagent: Can be used as a deuterated reagent or in deuterated solvents for nuclear magnetic resonance (NMR) spectroscopy applications.

Basic Information

Product Name	3-Aminopyridine-D6
CAS No.	1219805-61-4
Molecular Formula	C5D6N2
Molecular Weight	96.14 g/mol
Synonyms	3-Amino-D6-pyridine; Deuterated 3-Aminopyridine; 3-Pyridinamine-D6; 3-AP-D6; [D6]-3-Aminopyridine; 3-Aminopyridine (amino-D6); Pyridine-3-amine-D6; 3-Pyridylamine-D6
EINECS	Contact for details

Quality Control

Our 3-Aminopyridine-D6 is manufactured under strict quality management systems to ensure exceptional isotopic purity and chemical integrity. Each batch is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry to confirm deuterium incorporation and chemical purity. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and solvent residues is provided with every shipment, supporting compliance with research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (D-content)	≥98 atom % D
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.