Description

3-Pyrrolidinol-2,2,3,4,4-D5 is a deuterium-labeled analog of 3-pyrrolidinol, a versatile heterocyclic building block. This isotopically labeled compound is essential for advanced research and development, particularly in the fields of medicinal chemistry and analytical science. It is primarily used by pharmaceutical researchers, agrochemical developers, and contract research organizations (CROs) requiring high-fidelity internal standards and metabolic pathway tracers.

Application

• Internal Standard for Mass Spectrometry (MS): Used in quantitative bioanalytical methods (LC-MS/MS) for accurate measurement of 3-pyrrolidinol or related metabolites in complex biological matrices.
• Metabolic Pathway Tracing: Serves as a stable isotope tracer in pharmacokinetic (PK) and drug metabolism studies to elucidate metabolic profiles and degradation pathways.
• Pharmaceutical Intermediate: Acts as a deuterated synthon in the synthesis of novel Active Pharmaceutical Ingredients (APIs) and potential drug candidates for enhanced stability or metabolic studies.
• Agrochemical Research: Employed in the development and analysis of deuterated pesticides or herbicides to study environmental fate and degradation.
• NMR Spectroscopy: Useful as a probe in nuclear magnetic resonance (NMR) studies due to the distinct properties of deuterium atoms.
• Chemical Reference Standard: Provides a certified reference material for quality control and method validation in analytical laboratories.

Basic Information

Product Name	3-Pyrrolidinol-2,2,3,4,4-D5
CAS No.	1219805-52-3
Molecular Formula	C4H4D5NO
Molecular Weight	92.15 g/mol (approx.)
Synonyms	3-Hydroxypyrrolidine-d5; 3-Pyrrolidinol-d5; Pyrrolidin-3-ol-2,2,3,4,4-d5; (2,2,3,4,4-Pentadeuterio-3-pyrrolidinyl) alcohol; 3-Pyrrolidinol (2,2,3,4,4-d5); Deuterated 3-Pyrrolidinol; 3-Pyrrolidinol-D5; 3-Pyrrolidinol pentadeuterated
EINECS	Contact for details

Quality Control

Our deuterated chemicals are produced under strict quality control protocols to ensure high isotopic purity and chemical integrity. Each batch is characterized by advanced analytical techniques including NMR, MS, and HPLC. Certificates of Analysis (COA) are provided, detailing specifications for isotopic enrichment (D-atom %), chemical purity, and identity confirmation. We adhere to cGMP principles where applicable to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. Handle and store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Chemical Purity)
Isotopic Purity (MS)	≥ 98 atom % D
Water Content (KF)	≤ 1.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.