Description

n-Octanoylglycine-2,2-D2 is a deuterated derivative of octanoylglycine, a key metabolite in fatty acid oxidation pathways. This isotopically labeled compound is of critical importance for use as an internal standard in quantitative mass spectrometry, ensuring analytical accuracy and reproducibility. It is primarily needed by research scientists and quality control laboratories in the pharmaceutical, biotechnology, and clinical diagnostics sectors for metabolic studies and biomarker validation.

Application

• Mass Spectrometry Internal Standard: Essential for the precise quantification of octanoylglycine and related acylglycines in biological matrices via LC-MS/MS and GC-MS.
• Metabolomics Research: Used in stable isotope dilution analysis to investigate disorders of fatty acid metabolism, such as medium-chain acyl-CoA dehydrogenase (MCAD) deficiency.
• Biomarker Assay Development: Serves as a critical reference compound in the development and validation of clinical diagnostic assays for inborn errors of metabolism.
• Pharmacokinetic/Pharmacodynamic (PK/PD) Studies: Employed in drug development to track the modulation of specific metabolic pathways.
• Quality Control Reference Material: Used in analytical laboratories to calibrate instruments and verify method performance for acylglycine analysis.

Basic Information

Product Name	n-Octanoylglycine-2,2-D2
CAS No.	1219805-51-2
Molecular Formula	C₁₀H₁₇D₂NO₃
Molecular Weight	203.26 g/mol
Synonyms	Octanoylglycine-2,2-d2; N-Octanoyl-glycine-2,2-d2; Capryloylglycine-2,2-d2; 2-(Octanoylamino)acetic-2,2-d2 acid; Deuterated Octanoylglycine; (2,2-Dideutero-2-(octanoylamino)acetic acid); Internal Standard for Octanoylglycine
EINECS	Contact for details

Quality Control

Every batch of n-Octanoylglycine-2,2-D2 is produced and analyzed under strict quality management protocols. We ensure high chemical and isotopic purity through advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA), detailing purity, isotopic enrichment, and solvent content, is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.