Description

Iso‐Butyl 4‐Hydroxybenzoate‐2,3,5,6‐D4 is a deuterium-labeled isotopologue of the common preservative and pharmaceutical intermediate, isobutylparaben. This compound matters for researchers and manufacturers requiring high-precision analytical standards for quantitative mass spectrometry, metabolic studies, and pharmacokinetic research. It is primarily needed by the pharmaceutical, biotechnology, and analytical chemistry industries for use as an internal standard in LC-MS/MS and GC-MS methods to ensure accurate and reliable data.

Application

• As a stable isotope-labeled internal standard for the quantification of isobutylparaben in complex biological and environmental matrices via LC-MS/MS or GC-MS.
• In pharmacokinetic and metabolic studies to track the absorption, distribution, metabolism, and excretion (ADME) of parabens in vivo.
• For method development and validation in analytical laboratories to improve assay accuracy, precision, and regulatory compliance.
• In environmental monitoring research to precisely measure paraben contamination levels in water, soil, and consumer products.
• As a critical reagent in deuterium-labeled compound synthesis for more complex isotopically labeled molecules.
• For quality control and assurance in pharmaceutical manufacturing where parabens are used as preservatives in formulations.

Basic Information

Product Name	Iso‐Butyl 4‐Hydroxybenzoate‐2,3,5,6‐D4
CAS No.	1219805-33-0
Molecular Formula	C11H10D4O3
Molecular Weight	194.25 g/mol
Synonyms	Isobutylparaben-d4; 4-Hydroxybenzoic Acid Isobutyl Ester-2,3,5,6-d4; Deuterated Isobutyl Paraben; Isobutyl 4-Hydroxybenzoate-d4; 2,3,5,6-Tetradeutero-4-hydroxybenzoic Acid Isobutyl Ester; Isobutyl Paraben (phenyl-d4); Isobutyl p-Hydroxybenzoate-d4
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced under strict quality control protocols to ensure high chemical and isotopic purity, which is critical for analytical applications. Each batch is characterized by NMR, HPLC, and mass spectrometry to confirm identity, chemical purity, and deuterium incorporation. Certificates of Analysis (COA) detailing lot-specific data are available upon request, supporting compliance with GLP and ISO 17025 standards for reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Chemical Purity (by HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.