Description

Methyl-d3 (CAS NO 1219805-23-8) is a stable isotope-labeled compound where three hydrogen atoms are replaced by deuterium. This deuterated analog is a critical tool for analytical chemistry, providing an internal standard for precise quantification and metabolic pathway tracing. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors who require high-purity, well-characterized reference materials for mass spectrometry and NMR studies.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative internal standard in LC-MS and GC-MS analyses to enhance accuracy and reproducibility in pharmacokinetic and metabolomic studies.
• NMR Spectroscopy Solvent & Reagent: Serves as a deuterated solvent or a tracer in nuclear magnetic resonance (NMR) spectroscopy for structural elucidation and reaction monitoring.
• Pharmaceutical Research & Development: Employed in the synthesis of deuterated drug candidates for improved metabolic stability and in drug metabolism and pharmacokinetics (DMPK) studies.
• Metabolic Pathway Analysis: Acts as a stable isotopic tracer to investigate biochemical pathways and mechanisms in biological systems.
• Chemical Synthesis Intermediate: Utilized as a building block for synthesizing more complex deuterated compounds for research and specialty material production.
• Environmental & Forensic Analysis: Applied in isotope dilution methods for the sensitive and accurate detection of contaminants or compounds in complex matrices.

Basic Information

Product Name	Methyl-d3
CAS No.	1219805-23-8
Molecular Formula	CD3H (often represented for the methyl-d3 group)
Molecular Weight	Contact for details
Synonyms	Deuterated Methyl; Trideuteriomethane; Methyl-d3; (2H3)Methane; Perdeuterated Methyl Group; CD3H; Methyl-2H3; Methane-d3
EINECS	Contact for details

Quality Control

Every batch of Methyl-d3 is produced and analyzed under strict quality management protocols. We ensure high isotopic purity and chemical purity through advanced analytical techniques including NMR and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, assay, and impurity profiles is provided with each shipment to guarantee consistency and reliability for your critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and gaseous nature under standard conditions, this material must be stored in a certified gas cylinder or appropriate sealed vessel in a cool, well-ventilated area. Keep away from heat, sparks, and open flames. Specific storage temperature and pressure conditions are provided on the material safety data sheet (MSDS).

Specification

Item	Specification
Appearance	Colorless Gas
Identification (NMR)	Conforms
Isotopic Purity (D)	≥ 99.0 atom % D
Isotopic Purity (Methyl-d3)	≥ 98.0%
Chemical Purity (GC)	≥ 99.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.