Description

4-Chloroanisole--D4 is a deuterium-labeled isotopologue of 4-chloroanisole, a key aromatic ether compound. This stable isotope-labeled version is essential for applications requiring precise internal standards in quantitative mass spectrometry, ensuring accurate and reliable analytical results. It is primarily utilized by research and development laboratories, pharmaceutical companies, and analytical service providers in the fields of metabolite identification, pharmacokinetic studies, and environmental analysis.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a critical reference compound in GC-MS and LC-MS/MS for the accurate quantification of 4-chloroanisole and related metabolites.
• Pharmaceutical Research & Development: Used in drug metabolism and pharmacokinetics (DMPK) studies to track the fate of parent compounds and identify metabolites.
• Environmental Analysis: Enables precise measurement of chlorinated anisole derivatives as environmental contaminants or degradation products in complex matrices.
• Chemical Synthesis Tracing: Acts as a labeled precursor or tracer in mechanistic studies and synthetic pathway analysis.
• Forensic and Regulatory Testing: Provides a reliable standard for method validation and compliance testing in regulated laboratories.
• Academic Research: Supports fundamental research in organic chemistry, isotope effects, and analytical method development.

Basic Information

Product Name	4-Chloroanisole--D4
CAS No.	1219804-86-0
Molecular Formula	C7H3D4ClO
Molecular Weight	144.61 g/mol (approx.)
Synonyms	1-Chloro-4-methoxybenzene-d4; p-Chloroanisole-d4; 4-Methoxychlorobenzene-d4; Deuterated 4-Chloroanisole; 4-Chloromethoxybenzene-d4; Anisole, 4-chloro-, ring-d4; (2,3,5,6-D4)-4-Chloroanisole
EINECS	Contact for details

Quality Control

Our 4-Chloroanisole--D4 is produced under controlled conditions to ensure high isotopic purity and chemical integrity. Each batch undergoes rigorous quality testing, including analysis by NMR and mass spectrometry, to confirm isotopic enrichment and chemical purity. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed when not in use to prevent evaporation and potential concentration changes.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR / NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (Chemical)
Isotopic Purity (MS)	≥ 98 atom % D
Isotopic Enrichment	≥ 99% (D4)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.