Description

5-(Methoxy-D3)-2-Mercaptobenzimidazole is a deuterated derivative of the versatile benzimidazole scaffold, specifically labeled with a deuterated methoxy group. This compound is of significant value for its utility as a stable isotope-labeled internal standard in advanced analytical chemistry, ensuring precise quantification and method validation. It is primarily needed by research and development laboratories in the pharmaceutical, agrochemical, and material science industries for applications in mass spectrometry, metabolic studies, and quality control of complex formulations.

Application

• As a stable isotope-labeled internal standard (SIL-IS) for the accurate quantification of its non-deuterated counterpart or related metabolites in bioanalytical methods using LC-MS/MS.
• For pharmacokinetic and metabolic stability studies in drug discovery and development, aiding in the understanding of drug absorption, distribution, metabolism, and excretion (ADME).
• In method development and validation within quality control laboratories to enhance the accuracy, precision, and reliability of analytical assays.
• As a key chemical reference standard for calibrating instruments and verifying the purity of commercial batches of 2-mercaptobenzimidazole derivatives.
• For research into deuterium isotope effects in chemical reactions and material properties, relevant in advanced organic synthesis and material science.
• Potential use in the synthesis of more complex deuterated compounds for specialized research applications in photovoltaics or as tracers.

Basic Information

Product Name	5-(Methoxy-D3)-2-Mercaptobenzimidazole
CAS No.	1219804-80-4
Molecular Formula	C8H5D3N2OS
Molecular Weight	167.22 g/mol
Synonyms	2-Mercapto-5-(trideuteriomethoxy)-1H-benzimidazole; 5-(Methoxy-d3)-1H-benzimidazole-2-thiol; Deuterated 2-Mercaptobenzimidazole; 2-Thiol-5-(methoxy-d3)benzimidazole; 5-(CD3O)-2-MBI; 2-Benzimidazolethiol, 5-(methoxy-d3)-; 1219804-80-4; 5-(Trideuteriomethoxy)-2-mercaptobenzimidazole
EINECS	Contact for details

Quality Control

Our 5-(Methoxy-D3)-2-Mercaptobenzimidazole is produced under strict quality management protocols to ensure high chemical and isotopic purity, which is critical for its function as an analytical standard. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, isotopic enrichment, and impurity profile. We adhere to relevant industry standards for reference materials, and specifications can be tailored to meet specific research or compendial requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere for long-term preservation. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (D3)	≥ 98 atom % D
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.