Description

N,N'-Bis(3-Aminopropyl-D6)-1,3-Propanediamine is a deuterated analog of the polyamine spermidine, where six hydrogen atoms are replaced with deuterium. This compound is a critical stable-isotope labeled building block for advanced research and development. It is primarily utilized by scientists in pharmaceutical discovery, metabolic research, and analytical chemistry who require high-purity, isotopically labeled compounds for precise tracing and quantification studies.

Application

• Internal Standard for Mass Spectrometry: Used as a quantitative reference standard in LC-MS and GC-MS analysis of polyamines and related metabolites.
• Metabolic Pathway Tracing: Enables the study of polyamine biosynthesis, catabolism, and cellular uptake in biological systems using deuterium as a stable tracer.
• Pharmaceutical Research: Serves as a labeled precursor or intermediate in the synthesis of deuterated drug candidates for improved pharmacokinetic studies.
• Biochemical Assay Development: Employed in the creation of sensitive and specific diagnostic assays for polyamine-related disorders.
• NMR Spectroscopy: Useful as a deuterated standard or solvent shift reagent in nuclear magnetic resonance studies.

Basic Information

Product Name	N,N'-Bis(3-Aminopropyl-D6)-1,3-Propanediamine
CAS No.	1219804-74-6
Molecular Formula	C9D6H18N4
Molecular Weight	206.34 g/mol
Synonyms	N1,N4-Bis(3-aminopropyl-D6)-1,4-diaminobutane; Spermidine-d6; 1,5,10-Triazadecane-1,1,2,2,9,9,10,10-d8; N-(3-Aminopropyl-D3)-1,4-diaminobutane-D3; Deuterated Spermidine; Bis(3-aminopropyl-D3)amine; 1,4-Bis(3-aminopropyl-D3)butanediamine; Isotope Labeled Polyamine
EINECS	Contact for details

Quality Control

Our N,N'-Bis(3-Aminopropyl-D6)-1,3-Propanediamine is manufactured under strict quality systems to ensure high isotopic purity and chemical integrity, essential for sensitive research applications. Each batch is analyzed by NMR and Mass Spectrometry to confirm deuterium incorporation and chemical purity. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically >98 atom % D), purity, and analytical methods is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive). For long-term storage, consider sealing under an inert atmosphere such as argon or nitrogen to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Purity (MS)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.