Description

2,4,5-Trichloroaniline-D4 is a deuterium-labeled isotopologue of 2,4,5-trichloroaniline, a key intermediate in chemical synthesis. This stable isotope-labeled compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring high analytical accuracy and traceability. It is primarily required by research institutions, pharmaceutical companies, and analytical laboratories engaged in method development, environmental monitoring, and metabolism studies.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a critical reference compound in LC-MS and GC-MS analysis for the quantification of 2,4,5-trichloroaniline and related metabolites.
• Pharmaceutical Research: Used in drug metabolism and pharmacokinetics (DMPK) studies to track the fate of parent compounds and their degradation pathways.
• Environmental Analysis: Enables precise measurement of chlorinated aniline residues and their breakdown products in soil, water, and biological samples.
• Chemical Synthesis Tracing: Acts as a labeled precursor or tracer in synthetic chemistry to elucidate reaction mechanisms and pathways.
• Regulatory Compliance Testing: Supports analytical methods for compliance with environmental and food safety regulations concerning chlorinated aromatic amines.
• Isotope Dilution Analysis: Fundamental for high-precision analytical techniques that correct for sample loss and matrix effects.

Basic Information

Item	Details
Product Name	2,4,5-Trichloroaniline-D4
CAS No.	1219804-61-1
Molecular Formula	C6H2D4Cl3N
Molecular Weight	~214.49 g/mol
Synonyms	2,4,5-Trichloroaniline-d4; Deutero-2,4,5-Trichloroaniline; 1-Amino-2,4,5-trichlorobenzene-d4; 2,4,5-Trichloro-[2,3,5,6-2H4]aniline; 2,4,5-Trichlorophenylamine-d4; Perdeuterated 2,4,5-Trichloroaniline (D4); TCA-d4; 2,4,5-TCA-d4
EINECS	Contact for details

Quality Control

Our 2,4,5-Trichloroaniline-D4 is manufactured under strict quality control protocols to ensure high isotopic purity and chemical integrity, suitable for sensitive analytical applications. Each batch is characterized by advanced spectroscopic and chromatographic methods, including NMR, HPLC, and MS, to confirm isotopic enrichment and chemical purity. A comprehensive Certificate of Analysis (COA) detailing isotopic purity (e.g., D-atom %), chemical purity, and solvent content is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98.0 atom % D
Chemical Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.