Description

Cyclopropane-D5-Carboxylic Acid is a stable isotope-labeled analog of cyclopropanecarboxylic acid, where five hydrogen atoms are replaced by deuterium. This high isotopic purity is critical for applications requiring precise internal standards and metabolic pathway tracing in advanced analytical research. It is an essential building block for pharmaceutical, agrochemical, and material science R&D, particularly in the synthesis of labeled compounds for mass spectrometry and NMR spectroscopy.

Application

• Internal Standard for LC-MS/MS and GC-MS: Used as a quantitative reference standard in bioanalytical method development for drug metabolism and pharmacokinetics (DMPK) studies.
• Metabolic Pathway Tracing: Enables the investigation of biochemical pathways and metabolite identification in pharmaceutical and environmental research.
• Synthetic Intermediate for Labeled Compounds: Serves as a key precursor in the synthesis of deuterium-labeled active pharmaceutical ingredients (APIs) and agrochemicals.
• NMR Spectroscopy Solvent & Reagent: Utilized as a probe or shift reagent in nuclear magnetic resonance studies due to its distinct spectroscopic properties.
• Isotope Dilution Mass Spectrometry (IDMS): Provides high accuracy and precision in quantitative analysis for clinical diagnostics and environmental testing.
• Research in Material Science: Used in the development of novel organic electronic materials and polymers where deuterium incorporation modifies physical properties.

Basic Information

Product Name	Cyclopropane-D5-Carboxylic Acid
CAS No.	1219804-09-7
Molecular Formula	C4D5HO2
Molecular Weight	91.12 g/mol (for C4D5HO2)
Synonyms	Cyclopropanecarboxylic-d5 acid; (2H5)Cyclopropanecarboxylic Acid; Perdeuterated Cyclopropanecarboxylic Acid; Cyclopropane-1,2,2,3,3-d5-carboxylic Acid; Cyclopropanecarboxylic Acid-d5; Cyclopropanecarboxylic Acid (D5); Cyclopropanecarboxylic-2,2,3,3,1-d5 Acid
EINECS	Contact for details

Quality Control

Our Cyclopropane-D5-Carboxylic Acid is manufactured under strict quality systems to ensure exceptional isotopic and chemical purity for research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic purity (D-enrichment), chemical purity by HPLC, and identity confirmation. We adhere to cGMP principles where applicable, and our quality commitment ensures reliable, reproducible performance as a critical analytical standard.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR / NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.