Description

p-Tolualdehyde-2,3,5,6-D4 is a deuterated derivative of p-tolualdehyde, a valuable isotopically labeled compound used as a critical internal standard and tracer in advanced analytical chemistry. This high-purity material is essential for ensuring accuracy and reliability in quantitative mass spectrometry and NMR spectroscopy, where non-labeled compounds can lead to analytical interference. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, agrochemical, and material science industries for method development, metabolic studies, and precise quantification.

Application

• Internal Standard for GC-MS and LC-MS analysis in pharmaceutical impurity profiling and bioanalytical studies.
• Deuterated tracer in metabolic pathway research and drug metabolism/pharmacokinetics (DMPK) investigations.
• Critical reagent for quantitative NMR (qNMR) spectroscopy, providing a stable reference for purity determination.
• Building block for the synthesis of deuterated fine chemicals and advanced materials requiring isotopic labeling.
• Use in environmental analysis as a labeled standard for detecting and quantifying aromatic aldehydes in complex matrices.
• Substrate for mechanistic studies in organic chemistry and catalysis, leveraging kinetic isotope effects.

Basic Information

Product Name	p-Tolualdehyde-2,3,5,6-D4
CAS No.	1219804-07-5
Molecular Formula	C8D4H4O
Molecular Weight	124.17 g/mol
Synonyms	4-Methylbenzaldehyde-2,3,5,6-D4; p-Methylbenzaldehyde-D4; 4-Formyltoluene-D4; Deutero-p-tolualdehyde; (2,3,5,6-D4)-4-Methylbenzaldehyde; Toluene-4-carboxaldehyde-2,3,5,6-D4; 4-(Dideuteriomethyl)benzaldehyde-2,3,5,6-D4
EINECS	Contact for details

Quality Control

Our p-Tolualdehyde-2,3,5,6-D4 is manufactured under strict quality systems to ensure high isotopic purity and chemical integrity, meeting the stringent requirements of analytical and research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (D atom %), chemical purity, and identity confirmation. We adhere to relevant industry standards for labeled compounds, and custom specifications or GMP-grade material can be discussed based on project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC or HPLC)	≥ 98.0%
Isotopic Purity (D atom %)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.