Description

(±)-Epinephrine-D6 CAS NO 1219803-77-6 is a stable isotope-labeled analog of the critical neurotransmitter and hormone, epinephrine. This deuterated compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring the highest accuracy and reliability in analytical measurements. It is primarily required by pharmaceutical R&D laboratories, clinical research facilities, and contract research organizations (CROs) for drug metabolism, pharmacokinetic studies, and bioanalytical method development.

Application

• Internal Standard for LC-MS/MS: Critical for the precise quantification of endogenous epinephrine levels in complex biological matrices like plasma, serum, and urine.
• Drug Metabolism and Pharmacokinetics (DMPK): Used in tracer studies to investigate the absorption, distribution, metabolism, and excretion (ADME) profiles of epinephrine and related compounds.
• Clinical Research and Diagnostics: Enables accurate measurement of catecholamine levels in studies related to stress, cardiovascular diseases, and pheochromocytoma diagnosis.
• Bioanalytical Method Development and Validation: Serves as a reference standard to establish specificity, accuracy, and precision in new analytical protocols.
• Pharmaceutical Quality Control: Can be utilized in the analysis of epinephrine-containing pharmaceutical formulations to ensure potency and purity.
• Forensic Toxicology: Aids in the definitive identification and quantification of epinephrine in forensic casework.

Basic Information

Product Name	(±)-Epinephrine-D6
CAS No.	1219803-77-6
Molecular Formula	C9H7D6NO3
Molecular Weight	189.23 g/mol
Synonyms	Adrenaline-d6; DL-Epinephrine-2,5,6-α,β,β-d6; 4-[1-Hydroxy-2-(methylamino)ethyl]benzene-1,2-diol-d6; (±)-3,4-Dihydroxy-α-[(methylamino)methyl]benzyl alcohol-d6; Racemic Epinephrine-d6; Deuterated Epinephrine; Epinephrine Internal Standard
EINECS	Contact for details

Quality Control

Our (±)-Epinephrine-D6 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical and isotopic purity suitable for sensitive analytical applications. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and solvent content is provided with every shipment to guarantee traceability and consistency for your research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC-MS)	Conforms
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.