Description

Ethyl-D5 4-Aminobenzoate is a deuterated derivative of ethyl 4-aminobenzoate, a compound of significant interest in analytical and synthetic chemistry. This deuterium-labeled version is specifically designed for use as an internal standard in mass spectrometry and other quantitative analytical techniques, ensuring high accuracy and reliability in trace analysis. It is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and academic sectors who require precise measurement of the parent compound or its metabolites.

Application

• Primary use as an internal standard for the quantification of ethyl 4-aminobenzoate (benzocaine) and related compounds via LC-MS/MS and GC-MS.
• Critical component in deuterium labeling studies and metabolic pathway research within pharmaceutical development.
• Used in the synthesis of deuterated analogs of pharmaceutical intermediates for drug discovery and development.
• Applied in stable isotope dilution analysis to ensure accuracy in environmental and food safety testing.
• Valuable for method development and validation in analytical laboratories to meet regulatory compliance (e.g., FDA, EMA).
• Employed in academic and industrial research investigating the pharmacokinetics and bioavailability of local anesthetics.

Basic Information

Product Name	Ethyl-D5 4-Aminobenzoate
CAS No.	1219803-76-5
Molecular Formula	C9D5H4NO2
Molecular Weight	169.19 g/mol
Synonyms	Benzocaine-d5; Ethyl 4-Aminobenzoate-d5; Ethyl p-Aminobenzoate-d5; 4-(Amino-d2)benzoic Acid Ethyl-d3 Ester; Deutero-Benzocaine; Benzocaine (ethyl-d5, amino-d2); p-Aminobenzoic Acid Ethyl-d5 Ester
EINECS	Contact for details

Quality Control

Our Ethyl-D5 4-Aminobenzoate is produced under controlled conditions to ensure high chemical and isotopic purity, critical for its role as an analytical standard. Each batch undergoes rigorous testing, including NMR, HPLC, and mass spectrometry, to confirm identity, chemical purity, and deuterium enrichment. A comprehensive Certificate of Analysis (COA) detailing isotopic purity (e.g., D-atom %), chemical assay, and impurity profile is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Chemical Purity (NMR)	Conforms
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.