Description

Ethyl 4-Piperidinecarboxylate--D9 is a deuterated derivative of ethyl isonipecotate, a valuable building block in organic synthesis. This isotopically labeled compound is essential for creating internal standards and labeled analogs used in advanced analytical and pharmacological research. It is primarily utilized by pharmaceutical R&D teams and analytical laboratories engaged in drug metabolism and pharmacokinetics (DMPK) studies, proteomics, and the development of novel active pharmaceutical ingredients (APIs).

Application

• As a deuterated internal standard for the precise quantification of ethyl isonipecotate and related metabolites in bioanalytical assays using LC-MS/MS.
• In the synthesis of deuterium-labeled pharmaceutical intermediates for drug discovery programs, enhancing metabolic stability studies.
• For isotope dilution mass spectrometry applications to ensure accuracy and reliability in complex sample matrices.
• As a key precursor in medicinal chemistry for the development of labeled target molecules in neurological and cardiovascular research.
• In proteomics and metabolomics research as a stable isotope-labeled tracer.
• For academic and industrial R&D focused on understanding reaction mechanisms using isotopic labeling.

Basic Information

Product Name	Ethyl 4-Piperidinecarboxylate--D9
CAS No.	1219803-75-4
Molecular Formula	C8D9H6NO2
Molecular Weight	~157.21 g/mol
Synonyms	Ethyl 4-Piperidinecarboxylate-d9; Ethyl Isonipecotate-d9; Ethyl Piperidine-4-carboxylate-d9; 4-(Ethoxycarbonyl)piperidine-d9; NSC 172112-d9; 1,2,3,4,5,6,7,8,9-D9-Ethyl piperidine-4-carboxylate; Ethyl 4-Piperidinecarboxylate (Deuterated)
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced under strict quality protocols to ensure high isotopic purity and chemical integrity, critical for sensitive analytical applications. Each batch is characterized by advanced spectroscopic methods, including NMR and Mass Spectrometry, to confirm deuteration level and chemical purity. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (e.g., D-atom %), chemical purity, and analytical data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-atom %)	≥ 98.0%
Deuteration Degree (MS)	≥ 99% D9
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.