Description

1-Bromo-2,6-Difluorobenzene-D3 is a deuterated aromatic compound where three hydrogen atoms are replaced by deuterium, serving as a stable isotope-labeled analog of 1-bromo-2,6-difluorobenzene. This deuteration is critical for applications requiring minimal interference from background signals, providing enhanced analytical precision and metabolic stability in research. It is an essential building block and internal standard for scientists and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for drug discovery and development processes.

Application

• Pharmaceutical Research & Development: Used as a stable isotope-labeled internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the quantitative bioanalysis of drugs and metabolites.
• Metabolic Studies: Employed in pharmacokinetic and drug metabolism studies to trace metabolic pathways and improve the detection limits of analytical methods.
• Agrochemical Development: Acts as a key deuterated intermediate in the synthesis of novel, labeled pesticides and herbicides for environmental fate and residue analysis.
• Organic Synthesis: Serves as a versatile, deuterated building block for synthesizing complex molecules in medicinal chemistry, enabling the incorporation of deuterium for property modulation.
• Material Science: Utilized in the development of specialty polymers and advanced organic electronic materials where isotopic labeling is required for structural analysis.
• NMR Spectroscopy: Functions as a useful probe or solvent additive in Nuclear Magnetic Resonance (NMR) spectroscopy due to its distinct isotopic signature.

Basic Information

Item	Detail
Product Name	1-Bromo-2,6-Difluorobenzene-D3
CAS No.	1219803-73-2
Molecular Formula	C6H2D3BrF2
Molecular Weight	195.99 g/mol (approx.)
Synonyms	2,6-Difluorobromobenzene-D3; 2-Bromo-1,3-Difluorobenzene-D3; Benzene-D3, 1-bromo-2,6-difluoro-; [2H3]-1-Bromo-2,6-difluorobenzene; Deutero-1-Bromo-2,6-difluorobenzene; 1-Bromo-2,6-difluoro(benzene-d3); Bromodifluorobenzene-D3
EINECS	Contact for details

Quality Control

Our 1-Bromo-2,6-Difluorobenzene-D3 is produced under stringent conditions to ensure high isotopic and chemical purity, meeting the exacting requirements of research and industrial applications. Each batch undergoes comprehensive analysis, including NMR, GC-MS, and HPLC, to verify identity, chemical purity, and deuterium enrichment. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance with your quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 98.0%
Deuterium Enrichment (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.