Description

2-Oxopiperazine--D6 is a deuterium-labeled analog of 2-oxopiperazine, a key heterocyclic scaffold. This stable isotope-labeled compound is essential for applications requiring high sensitivity and specificity in analytical detection and metabolic studies. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors for use as an internal standard in mass spectrometry, pharmacokinetic research, and the development of novel active pharmaceutical ingredients (APIs).

Application

• Internal Standard for Quantitative Analysis: Serves as a critical deuterated internal standard in LC-MS/MS and GC-MS methods for the accurate quantification of 2-oxopiperazine and related compounds in complex matrices.
• Drug Metabolism and Pharmacokinetics (DMPK): Used in tracer studies to investigate the absorption, distribution, metabolism, and excretion (ADME) profiles of drug candidates.
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of process-related impurities and degradants during API development and quality control.
• Biochemical Research: Employed as a tool in mechanistic studies of enzymatic reactions and metabolic pathways where the piperazine moiety is involved.
• Synthesis of Labeled Compounds: Acts as a deuterated building block for the synthesis of more complex isotopically labeled molecules for research and diagnostic purposes.

Basic Information

Product Name	2-Oxopiperazine--D6
CAS No.	1219803-71-0
Molecular Formula	C4H2D6N2O
Molecular Weight	118.17 g/mol
Synonyms	2-Piperazinone-d6; 2-Ketopiperazine-d6; 1,4-Diazacyclohexan-2-one-d6; Hexadeutero-2-oxopiperazine; Deuterated 2-oxopiperazine; Piperazin-2-one-d6; 2-Oxopiperazine (hexadeutero); 2,3,5,6-Tetradeutero-2,3,5,6-tetrahydropyrazine-1,4-d2-one
EINECS	Contact for details

Quality Control

Our 2-Oxopiperazine--D6 is manufactured under controlled conditions to ensure high isotopic purity and chemical integrity. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and mass spectrometry, to confirm identity, chemical purity, and deuterium enrichment. Certificates of Analysis (COA) detailing all specifications are provided to guarantee traceability and batch-to-batch consistency for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.