Description

(±)-3-Amino-Iso-Butyric-2,3,3-D3 Acid is a deuterium-labeled isotopologue of 3-aminoisobutyric acid, a key intermediate in valine and thymine catabolism. This compound is specifically engineered for use as an internal standard in mass spectrometry, enabling precise quantification and metabolic pathway tracing in complex biological matrices. It is an essential tool for researchers and quality control laboratories in the pharmaceutical, biotechnology, and clinical diagnostics sectors requiring high-fidelity analytical data.

Application

• Mass Spectrometry Internal Standard: Used for the accurate quantification of endogenous 3-aminoisobutyric acid (BAIBA) in biological samples via LC-MS/MS and GC-MS.
• Metabolic Pathway Research: A critical tracer for studying the catabolism of valine and thymine, and the role of BAIBA as an exercise-induced myokine.
• Pharmaceutical Development: Employed in pharmacokinetic (PK) and pharmacodynamic (PD) studies for drugs targeting metabolic disorders.
• Clinical Diagnostics: Serves as a reference standard in assays for inborn errors of metabolism, such as methylmalonic acidemia.
• Stable Isotope Labeling: Used in the synthesis of more complex deuterated compounds for advanced research applications.
• Biomarker Discovery & Validation: Facilitates the precise measurement of BAIBA levels in studies investigating its association with insulin sensitivity and cardiometabolic health.

Basic Information

Product Name	(±)-3-Amino-Iso-Butyric-2,3,3-D3 Acid
CAS No.	1219803-65-2
Molecular Formula	C4H6D3NO2
Molecular Weight	106.13 g/mol
Synonyms	(±)-3-Aminoisobutyric-2,3,3-d3 Acid; DL-3-Aminoisobutyric-2,3,3-d3 Acid; BAIBA-d3; 3-Amino-2-methylpropionic-2,3,3-d3 Acid; (RS)-3-Aminoisobutyric-2,3,3-d3 Acid; 3-Amino-2-methylpropanoic-2,3,3-d3 Acid; β-Aminoisobutyric-2,3,3-d3 Acid; 2-Methyl-β-alanine-2,3,3-d3
EINECS	Contact for details

Quality Control

Our (±)-3-Amino-Iso-Butyric-2,3,3-D3 Acid is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including NMR and mass spectrometry, to confirm isotopic enrichment and chemical purity. We provide comprehensive Certificates of Analysis (COA) detailing assay, isotopic purity, and impurity profiles. Our quality commitment ensures consistency and reliability for your critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 98 atom % D
Chemical Purity (Titration)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.