Description

4-Aminopiperidine--D5 is a deuterated analog of 4-aminopiperidine, a versatile building block in organic synthesis. This isotopically labeled compound is critical for creating internal standards and stable isotope-labeled tracers used in advanced analytical and pharmacological research. It is primarily utilized by pharmaceutical R&D teams, contract research organizations (CROs), and analytical laboratories engaged in drug metabolism and pharmacokinetics (DMPK) studies, proteomics, and mass spectrometry.

Application

• Internal Standard for Mass Spectrometry: Serves as a crucial quantitative reference in LC-MS and GC-MS analysis for accurate measurement of 4-aminopiperidine and related compounds.
• Drug Metabolism & Pharmacokinetics (DMPK): Used in the synthesis of deuterated drug metabolites to study absorption, distribution, metabolism, and excretion (ADME) profiles.
• Proteomics & Biochemical Research: Acts as a precursor for labeling reagents or probes in quantitative proteomics and other isotope-dilution-based assays.
• Pharmaceutical R&D: Employed as a deuterated synthon in the discovery and development of novel active pharmaceutical ingredients (APIs), particularly for structure-activity relationship (SAR) studies.
• Analytical Reference Material: Provides a high-purity, characterized standard for method development, validation, and quality control in analytical laboratories.

Basic Information

Product Name	4-Aminopiperidine--D5
CAS No.	1219803-60-7
Molecular Formula	C5H5D5N2
Molecular Weight	107.18 g/mol
Synonyms	4-Amino-1-piperidine-d5; 4-Aminopiperidine-d5; Piperidin-4-amine-d5; 1-Piperidinamine-d5; 4-Piperidinamine-d5; Deuterated 4-Aminopiperidine; [2H5]-4-Aminopiperidine; 4-Aminopiperidine (amino-d5)
EINECS	Contact for details

Quality Control

Our 4-Aminopiperidine--D5 is manufactured under strict quality systems to ensure high isotopic purity and chemical integrity, essential for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (D-content), chemical purity, and identity confirmation. We adhere to cGMP principles for the production of research-grade labeled compounds, ensuring traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.