Description

Dimethyl 4,4'-Biphenyl-D8-Dicarboxylate is a high-purity, deuterated derivative of dimethyl biphenyl-4,4'-dicarboxylate, serving as a critical internal standard and analytical reference material. Its value lies in providing exceptional isotopic purity and structural stability for precise quantitative analysis in advanced research and development. This compound is essential for scientists and quality control laboratories in the pharmaceutical, agrochemical, and material science industries, particularly for method development and validation in mass spectrometry and NMR studies.

Application

• Primary use as a deuterated internal standard for the accurate quantification of its non-deuterated analogue or related compounds via LC-MS or GC-MS.
• Critical reference material in pharmaceutical research for studying the metabolism, pharmacokinetics, and stability of active pharmaceutical ingredients (APIs) containing biphenyl moieties.
• Advanced organic synthesis and labeling studies, enabling the tracing of molecular pathways and reaction mechanisms.
• Essential component in analytical method development and validation to ensure regulatory compliance (e.g., FDA, ICH guidelines) in quality control laboratories.
• Used in material science research for investigating polymers and liquid crystals where deuterated compounds provide contrast in spectroscopic analysis.

Basic Information

Product Name	Dimethyl 4,4'-Biphenyl-D8-Dicarboxylate
CAS No.	1219803-50-5
Molecular Formula	C₁₆D₈H₂O₄
Molecular Weight	284.33 g/mol
Synonyms	Dimethyl Biphenyl-4,4'-dicarboxylate-D8; Biphenyl-4,4'-dicarboxylic Acid Dimethyl Ester-D8; [D8]-Dimethyl 4,4'-Biphenyldicarboxylate; 4,4'-Biphenyldicarboxylic Acid Dimethyl Ester-d8; Deuteronated Dimethyl Biphenyl Dicarboxylate; D8-Dimethyl Biphenyl-4,4'-dicarboxylate; Internal Standard for Biphenyl Dicarboxylate Analysis
EINECS	Contact for details

Quality Control

Every batch of Dimethyl 4,4'-Biphenyl-D8-Dicarboxylate is produced and tested under strict quality management systems to ensure the highest isotopic and chemical purity required for analytical applications. Our products undergo rigorous quality testing, including NMR and mass spectrometry, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing isotopic enrichment, chemical purity, and analytical methods are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.