Description

4-(n-Butylamino--D7)Benzoic Acid is a deuterium-labeled derivative of a key benzoic acid intermediate, where seven hydrogen atoms are replaced with the stable isotope deuterium. This isotopic labeling is critical for enhancing the sensitivity and reliability of analytical methods, particularly in pharmacokinetic and metabolic studies. It is an essential material for researchers and manufacturers in the pharmaceutical and agrochemical industries who require high-purity internal standards and tracer molecules for mass spectrometry and NMR spectroscopy.

Application

• Internal Standard for LC-MS/MS: Used as a quantitative reference standard in bioanalytical method development for drug metabolism and pharmacokinetics (DMPK) studies.
• Metabolic Pathway Tracing: Serves as a stable isotope-labeled tracer to investigate the metabolic fate and degradation pathways of active compounds in biological systems.
• Pharmaceutical Impurity Profiling: Employed in the identification and quantification of process-related impurities and degradants during drug substance development.
• Agrochemical Research: Applied in environmental fate studies to track the distribution and breakdown of pesticide or herbicide compounds.
• NMR Spectroscopy Solvent: Can be utilized as a specialized reagent or shift reference in deuterated solvent systems for advanced structural analysis.
• Chemical Synthesis Intermediate: Acts as a building block for the synthesis of more complex deuterated molecules for research and development.

Basic Information

Product Name	4-(n-Butylamino--D7)Benzoic Acid
CAS No.	1219803-44-7
Molecular Formula	C11H8D7NO2
Molecular Weight	~198.27 g/mol
Synonyms	4-(Butylamino-d7)benzoic acid; Benzoic acid, 4-(butylamino-d7)-; 4-(n-Butyl-d7-amino)benzoic acid; Deutero-labeled 4-Butylaminobenzoic Acid; 4-(Aminobutyl-d7)benzoic acid; 4-Butylaminobenzoic Acid-d7; p-(Butylamino-d7)benzoic acid
EINECS	Contact for details

Quality Control

Our 4-(n-Butylamino--D7)Benzoic Acid is manufactured under strict quality systems to ensure high isotopic purity and chemical integrity, essential for analytical applications. Each batch is characterized by NMR, Mass Spectrometry, and HPLC to confirm deuterium incorporation and chemical purity. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically >98 atom % D), chemical purity, and analytical results is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which can affect stability and analytical performance. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.