Description

Phenothiazine-D8,Nh is a high-purity, deuterium-labeled derivative of the phenothiazine core structure, specifically designed for advanced analytical and research applications. This compound serves as a critical internal standard and reference material in quantitative mass spectrometry, enabling precise and reliable measurements in complex matrices. It is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and environmental science sectors who require the highest level of accuracy in method development and validation.

Application

• Internal Standard for LC-MS/MS: Primary application as a stable isotope-labeled internal standard for the accurate quantification of phenothiazine and its metabolites in pharmacokinetic and bioanalytical studies.
• Metabolite Tracing & Pathway Analysis: Used in drug metabolism and disposition (DMPK) research to trace metabolic pathways and identify degradation products.
• Pharmaceutical Impurity Profiling: Critical for developing and validating analytical methods to identify and quantify impurities and degradants in active pharmaceutical ingredients (APIs).
• Environmental Analysis: Employed as a reference standard in the detection and quantification of phenothiazine-derived compounds in environmental samples.
• Forensic Toxicology: Supports method development for the screening and confirmation of phenothiazine-class drugs in forensic investigations.
• Chemical Research & Synthesis: Serves as a specialized building block or tracer in synthetic organic chemistry and mechanistic studies.

Basic Information

Product Name	Phenothiazine-D8,Nh
CAS No.	1219803-41-4
Molecular Formula	C12D8N2S
Molecular Weight	204.31 g/mol
Synonyms	Deuterated Phenothiazine (D8); Phenothiazine-d8; 10H-Phenothiazine-1,2,3,4,6,7,8,9-d8; Phenothiazine (D8, ring); Phenothiazine-D8 (Nitrogen-H); Stable Isotope Labeled Phenothiazine; Phenothiazine Internal Standard (D8); [D8]Phenothiazine
EINECS	Contact for details

Quality Control

Every batch of Phenothiazine-D8,Nh is manufactured and analyzed under strict quality management systems to ensure exceptional isotopic purity and chemical integrity. Our products undergo rigorous quality testing, including advanced spectroscopic and chromatographic techniques, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and analytical methods is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.