Description

4-Methylcatechol-D8 is a deuterium-labeled isotopologue of 4-methylcatechol, a key compound in analytical chemistry and life science research. This stable isotope-labeled standard is essential for ensuring the accuracy and reliability of quantitative mass spectrometry analyses. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, environmental, and metabolic research sectors for use as an internal standard in LC-MS and GC-MS methods.

Application

• Internal Standard for Quantitative Analysis: Serves as a critical internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the precise quantification of 4-methylcatechol and related metabolites.
• Pharmaceutical Research: Used in drug metabolism and pharmacokinetics (DMPK) studies to track the biotransformation pathways of catechol-containing drug candidates.
• Biomarker Analysis: Enables accurate measurement of endogenous catecholamines and their metabolites in clinical and toxicological research for biomarker discovery and validation.
• Environmental Monitoring: Applied in the analysis of environmental samples for phenolic compounds and pollutants derived from industrial processes.
• Chemical Synthesis Research: Acts as a labeled precursor or intermediate in the synthesis of more complex deuterated molecules for mechanistic studies.
• Quality Control & Method Development: Essential for developing, validating, and maintaining robust analytical methods in contract research organizations (CROs) and regulatory testing labs.

Basic Information

Product Name	4-Methylcatechol-D8
CAS No.	1219803-18-5
Molecular Formula	C7D8O2
Molecular Weight	128.19 g/mol
Synonyms	4-Methylcatechol-d8; 1,2-Dihydroxy-4-methylbenzene-d8; 3,4-Dihydroxytoluene-d8; 4-Methyl-1,2-benzenediol-d8; 4-Methylpyrocatechol-d8; Homocatechol-d8; Deuterated 4-Methylcatechol; [D8]-4-Methylcatechol
EINECS	Contact for details

Quality Control

Our 4-Methylcatechol-D8 is manufactured under strict quality control protocols to ensure high isotopic purity and chemical integrity, suitable for sensitive analytical applications. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR and HPLC-MS, to confirm deuteration level and chemical purity. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically >98% D), chemical purity, and analytical results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Chemical Purity (by HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.