Description

(±)-2-Methylpiperazine--D7 CAS NO 1219802-98-8 is a deuterium-labeled analog of 2-methylpiperazine, a versatile heterocyclic amine building block. This isotopically labeled compound is essential for creating internal standards and labeled tracers used in advanced analytical and metabolic studies. It is primarily utilized by pharmaceutical researchers, analytical chemists, and contract research organizations (CROs) engaged in drug discovery, development, and bioanalytical method validation.

Application

• Deuterated Internal Standards: For precise quantification in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) analysis of pharmaceuticals and metabolites.
• Metabolic Pathway Tracing: Used in pharmacokinetic (PK) and absorption, distribution, metabolism, and excretion (ADME) studies to track drug fate in biological systems.
• Pharmaceutical Intermediate: Serves as a labeled precursor in the synthesis of deuterated active pharmaceutical ingredients (APIs) for clinical research.
• Proteomics & Biomarker Research: Enables accurate relative and absolute quantification in stable isotope labeling workflows.
• Chemical Reference Material: Provides a high-purity, isotopically characterized standard for method development and validation in regulatory environments.
• NMR Spectroscopy: Acts as a useful tool in nuclear magnetic resonance studies due to the distinct properties of deuterium atoms.

Basic Information

Product Name	(±)-2-Methylpiperazine--D7
CAS No.	1219802-98-8
Molecular Formula	C5H5D7N2
Molecular Weight	115.21 g/mol
Synonyms	2-Methylpiperazine-d7; Hexadeutero-2-methylpiperazine; 1,4-Dideutero-2-(trideuteromethyl)piperazine; (±)-2-Methylpiperazine-1,1,2,3,3,6,6-d7; 2-Methylpiperazine (methyl-d3, 1,1,3,3,6,6-d6); Deuterated 2-Methylpiperazine; 2-Methylpiperazine Internal Standard
EINECS	Contact for details

Quality Control

Our deuterated chemicals are produced and controlled under a strict quality management system to ensure high isotopic purity and chemical purity, critical for sensitive analytical applications. Each batch is analyzed by NMR, MS, and HPLC to confirm identity, isotopic enrichment (typically ≥98 atom % D), and chemical assay. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.