Description

1,1-Dimethylhydrazine-D8 Dcl is a high-purity, deuterated isotopologue of 1,1-dimethylhydrazine (UDMH), specifically labeled with eight deuterium atoms and supplied as the deuterium chloride salt. This compound is an essential internal standard and reference material for quantitative mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy, providing unmatched accuracy in trace analysis. It is primarily utilized by analytical laboratories, contract research organizations (CROs), and pharmaceutical R&D teams working on method development, pharmacokinetic studies, and metabolic profiling where precise quantification is critical.

Application

• Internal Standard for LC-MS/MS: Used as a stable isotope-labeled internal standard for the accurate quantification of 1,1-dimethylhydrazine and related hydrazine compounds in complex matrices.
• Metabolite Tracing & Pharmacokinetics: Enables precise tracking of drug metabolites and assessment of absorption, distribution, metabolism, and excretion (ADME) profiles in preclinical and clinical studies.
• Environmental & Industrial Hygiene Analysis: Critical for monitoring occupational exposure and environmental contamination from rocket propellant (UDMH) manufacturing and handling sites.
• NMR Spectroscopy Solvent & Reagent: Serves as a deuterated reagent or shift reference in advanced NMR experiments for structural elucidation.
• Forensic & Regulatory Toxicology: Supports method validation and compliance testing for agencies requiring high-confidence analytical data.
• Chemical Synthesis Research: Employed in mechanistic studies and synthetic pathways where deuterium labeling is necessary to investigate reaction kinetics or pathways.

Basic Information

Product Name	1,1-Dimethylhydrazine-D8 Dcl
CAS No.	1219802-85-3
Molecular Formula	C2D8N2 • DCl
Molecular Weight	117.64 g/mol (approx.)
Synonyms	UDMH-D8 Deuterium Chloride; Dimazine-D8 Dcl; N,N-Dimethylhydrazine-D8 Deuteriochloride; 1,1-Dimethylhydrazine-d8 hydrochloride; (Dimethyl-d6-amino)(-d2)amine Dcl; Asymmetric Dimethylhydrazine-D8 Dcl; Isotopic Internal Standard 1219802-85-3; Deuterated UDMH Dcl Salt
EINECS	Contact for details

Quality Control

Every batch of 1,1-Dimethylhydrazine-D8 Dcl is manufactured and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity, verified by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and impurity profiles is provided with each shipment to ensure traceability and compliance with your research or quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to prevent degradation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.