Description

4-Chlorobenzyl-D4 Chloride is a deuterium-labeled derivative of 4-chlorobenzyl chloride, a versatile chemical intermediate. This isotopically labeled compound is essential for creating internal standards used in quantitative mass spectrometry, ensuring high analytical accuracy and reliability. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry industries for drug metabolism studies, environmental analysis, and the synthesis of labeled target molecules.

Application

• Internal Standard for LC-MS/MS: Serves as a critical, isotopically pure reference standard for the precise quantification of 4-chlorobenzyl chloride and related metabolites in complex biological and environmental matrices.
• Pharmaceutical Research: Used in the synthesis of deuterium-labeled drug candidates and metabolites for pharmacokinetic (PK), pharmacodynamic (PD), and absorption, distribution, metabolism, and excretion (ADME) studies.
• Agrochemical Development: Employed in the creation of labeled standards for tracing and quantifying pesticides, herbicides, or their degradation products in environmental fate studies.
• Chemical Synthesis Intermediate: Acts as a specialized building block for introducing a deuterated 4-chlorobenzyl moiety into more complex organic molecules for mechanistic or labeling purposes.
• Forensic and Doping Control Analysis: Provides a reliable standard for confirmatory testing and accurate measurement of specific compounds in forensic toxicology and anti-doping laboratories.

Basic Information

Product Name	4-Chlorobenzyl-D4 Chloride
CAS No.	1219802-84-2
Molecular Formula	C7H3D4Cl2
Molecular Weight	163.06 g/mol (for C7H3D4Cl2)
Synonyms	1-(Chloromethyl)-4-chlorobenzene-D4; (4-Chlorophenyl)methyl-D4 chloride; alpha,alpha,alpha,4-Tetradeutero-4-chlorobenzyl chloride; p-Chlorobenzyl-D4 Chloride; 4-Chlorobenzyl Chloride-d4; Deutero-labeled 4-Chlorobenzyl Chloride; Benzene, 1-(chloromethyl)-4-chloro-, alpha,alpha,alpha,4-tetradeutero-
EINECS	Contact for details

Quality Control

Our deuterated chemicals are produced and analyzed under strict quality protocols to ensure isotopic and chemical purity meets the exacting requirements of analytical and synthetic applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing results for isotopic purity (D-enrichment), chemical purity (by GC or HPLC), and identity confirmation (by NMR and/or MS). We adhere to relevant industry standards for high-purity reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0% (chemical purity)
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.